Sara Ramírez is a Mexican-American actress and singer. She won the 2005 Tony Award for Best Performance by a Featured Actress in a Musical for her role as The Lady of the Lake in Monty Python's Spamalot, and is a member of the cast of Grey's Anatomy.

Ramírez was born in Mazatlán, Sinaloa, a beach resort on the Pacific coast of Mexico. Her father was Mexican and her mother was half Mexican and half Irish-American. Ramírez moved with her mother at age eight to Tierrasanta, in San Diego, California. After graduating from the San Diego School of Creative and Performing Arts in San Diego, California, she graduated from the Juilliard School in New York City, where she refined her skills as an actress.

She debuted on Broadway playing Wahzinak in Paul Simon's The Capeman (1998). In 1999, she appeared in The Gershwins' Fascinating Rhythm (1999) and received an Outer Critics Circle Award nomination for her role. She has also appeared in A Class Act (2001), Dreamgirls (2001), and she performed in The Vagina Monologues with Tovah Feldshuh and Suzanne Bertish.

Sara also appeared in the movie "You've Got Mail" as the check-out girl "Rose" on the cash-only till, who at first refused to serve Meg Ryan's character. She put on a Spanish accent for this performance.

Ramírez joined the cast of Grey's Anatomy in a recurring role as Dr. Calliope 'Callie' Torres in the show's second season. For the third season she became a series regular. On a special Grey's Anatomy themed episode of The Oprah Winfrey Show, she revealed that Abcloved her performance in Spamalot and offered her a role in any Abcshow she wanted, and she picked Grey's, of which she was a fan.

Ramírez speaks both Spanish and English fluently; however, she retains the Spanish pronunciation of her name.