Peter André was discovered on the Australian TV talent show New Faces in 1990. Australian music guru Molly Meldrum was one of the judges on the show and signed André up after seeing him do a Bobby Brown impression. In 1992, the debut single "Gimme Little Sign" was released, eventually peaking at #3 and lasting 31 weeks on the official ARIA Charts. In 1993, a self-titled album charted well in Australia, while the singles "Funky Junky" and "Let's Get It On/Do You Wanna Dance?" reached the Australian Top 20. In 1993, "Gimme Little Sign" picked up an ARIA Award as the highest selling single of the year.

André first had a top 50 single in the UK called "Only One", which reached number #16, and then gained further success with the song "Mysterious Girl" (featuring Bubbler Ranx), which reached #2 in the UK singles chart and #8 in Australia. He then had a #1 album Natural, and two UK #1 singles "Flava", and "I Feel You". However, after attempting to transform into an R&B artist rather than pop and releasing a few more singles, his success waned, with his second album Time only reaching #28. In 1998 he released his last single (a cover of the song "Kiss the Girl" from Disney's The Little Mermaid) before being dropped by his music label, and taking a long break from the charts, to look after his young children.

He also appeared on the Childliners record The Gift Of Christmas alongside acts such as Backstreet Boys Boyzone E.Y.C., Sean Maguire, Deuce, Ultimate Kaos, Let Loose, East 17, MN8, Michelle Gayle, Dannii Minogueand many more.

During this period he journeyed to Cyprus, later appearing on the British reality TV series I'm a Celebrity... Get Me Out of Here!. He then re-released his breakthrough hit "Mysterious Girl" in 2004, finally reaching #1 eight years after the 1996 re-release of the song (it had been released once before in 1995). This marked six years since his last chart appearance. He released a follow-up song, "Insania", which reached #3 in the UK in June 2004. A new album, entitled The Long Road Back, was also released that month, however only reached #44. The next single from the album was "The Right Way" and featured Jordan (Katie Prince) in the video. This reached #14 in September 2004.

André married Katie Priceon 10 September 2005 at Highclere Castle, Berkshire, UK, becoming stepfather to Price's son, Harvey. André and Price became the parents of a baby boy, Junior Savva Andreas, on 13 June 2005. Their daughter, Princess Tiaamii, was born on 29 June 2007.