Michelle Ryan is an English actress of Irish ancestry. She is probably best known for portraying the role of Zoe Slater on the BBC soap opera EastEnders. She also starred in the 2007 television series remake Bionic Woman, and more recently as wicked sorceress Nimueh in the 2008 BBC TV series Merlin.

Michelle Ryan was born in Enfield, Greater London, Middlesex and was a student at Chace Community School. A member of a local theatre group since she was 10, she was picked for her role in EastEnders when she was 15 and first appeared on the show in September 2000; for the part, she affected an East End cockney accent, rather than speaking her usual Received Pronunciation. In 2005, she announced she was leaving EastEnders to concentrate on work in theatre and films. She said that her involvement with the show served as a dress rehearsal for working on Bionic Woman.

Ryan got her first big break playing Sheylla Grands in the Series TV Show "Chosen Ones" in the 1st season. During summer 2005, Ryan appeared in a run of Who's the Daddy? at the King's Head Theatre; the play by Toby Young and Lloyd Evans is based on the David Blunkett paternity case.

Ryan auditioned to replace Billie Piperas the Doctor's companion in Doctor Who; however, Freema Agyeman was ultimately chosen for the role. She had a small role in an episode of Marple which screened in February 2006, and also appeared in a small independent film the same year, Cashback.

In early 2007, Ryan was seen as Maria in a new adaptation of Mansfield Park opposite Billie Piperfor ITV and also as Lila in the film I Want Candy, co-starring Carmen Electraand Mackenzie Crook In February 2007, it was announced that she had been cast as the lead in the new drama Bionic Woman. The series began airing in the United States on the broadcast network NBC in September 2007. Ryan affects an American accent for the role of Jaime Sommers, except in the episode "The Education of Jaime Sommers" in which her character goes under cover as an English transfer student at a university; for this episode, she uses an Oxfordshire accent instead of her natural London accent. She has had professional dance training and attributes to it helping her with the physically demanding stunts required for the show.

On Red Nose Day 2007, Ryan appeared in a brand new Mr. Bean sketch written and recorded for Comic Relief. She will shortly be seen in Flick, a new Welsh independent film co-starring Faye Dunaway and Leslie Phillips.

In May 2007, Ryan revealed she auditioned for the role of Vesper Lynd in Casino Royale, eventually given to Eva Greenthe previous year.

Prior to Bionic Woman, she appeared in Jekyll for the BBC, a modern day version of Strange Case of Dr Jekyll and Mr Hyde starring James Nesbitt. It began its six-episode run on 16 June 2007 and was released on DVD in the United States on 18 September 2007, one week prior to her debut in Bionic Woman.

Ryan is signed to Independent Models in London, and is also a patron of children's cancer charity CLIC Sargent. She has been among FHM's 100 Sexiest Women in 2002, 2004, 2005 (fourth, her highest ranking), and 2007.