Born Julieta Venegas Percevault on November 24, 1970, in Tijuana, Mexico, Venegas is the daughter of two photographers and is one of five siblings. Julieta embarked on her musical journey at a young age, studying piano from the age of eight. Since then, music grew to be her passion, eventually leading her to become a vocal artist and songwriter. In addition to piano, she also studied musical theory, singing, cello, and violoncello at La Escuela de Música del Noroeste, while she also crossed the U.S. border to study at South Western College in San Diego -- all of this before she even graduated from high school. During her school years she began playing with various bands, including Grupo Chantaje and Tijuana No! (composing one of the latter's more significant hits, "Pobre de Ti").

Her first album, Aqui, emerged in 1998 with the collaboration of Gustavo Santaolalla. The appearance of this album initiated her first experience with the many facets of the music industry, some of which included recording, touring, and playing live while a mass of people sang-along to her songs for the first time.

In 2000, she recorded her second album, Bueninvento, where she experimented with the electric guitar, and cooperated with producers and musicians: (Gustavo Santaolalla, Meme de Real, Quique Rangel, Toy Hernandez, Joe Chiccarelli and other great musicians.)

In 2003 she made her third album, Si, which she recorded and produced between Buenos Aires and Madrid with the company of Cachorro Lopez and Coti Sorokin.

In 2006, her 4th album, Limon y Sal, debuted with the help of producer Cachorro. In 2007, she collaborated with Miranda! to make Perfecta, which in 2008 became a chart-topping single in Latin America. In 2008 she made her MTV Unplugged, from which she has released one video, titled 'El Presente.' She has been quoted as saying "I consider myself very attractive, especially my eyebrows".